Risk of Cancer Subsequent to Low-Dose Radiation

Low-dose extrapolation of radiation-related cancer risk.

Radiation dose and subsequent risk for stomach cancer in long-term survivors of cervical cancer.

PURPOSE To assess the dose-response relationship for stomach cancer after radiation therapy for cervical cancer. METHODS AND MATERIALS We conducted a nested, matched case-control study of 201 cases and 378 controls among 53,547 5-year survivors of cervical cancer diagnosed from 1943 to 1995, from 5 international, population-based cancer registries. We estimated individual radiation doses to t...

Low-dose radiation cancer susceptibility models

the biological effects of low-dose radiation exposure are increasingly better understood, continued research is needed to develop better individual risk-based models. Human population exposures to low doses of ionizing radiation (defined by the US Department of Energy as less than 10 rem or 0.1 Sv) are increasing due to occupational exposures of nuclear plant workers, waste managers and medical...

Hormesis by Low Dose Radiation Effects: Low-Dose Cancer Risk Modeling Must Recognize Up-Regulation of Protection

References ...................................................................................... Abstract Ionizing radiation primarily perturbs the basic molecular level proportional to dose, with potential damage propagation to higher levels: cells, tissues, organs, and whole body. There are three types of defenses against damage propagation. These operate deterministically and below a certai...

Protective Effect of Low Dose Melatonin on Radiation-Induced Damage to Rat Liver

Background: Melatonin is a free radical scavenger. It has also antioxidant effects through its stimulatory actions on antioxidant system. Objective: We conducted this study to examine the effect of different oral doses of melatonin on liver tissue. Methods: We used 42 rats—6 rats in each group. Group I served as the control group; group II rats were pretreated with only melatonin; group III w...